Effect of Defibrillation Pulses of Different Shapes on Biomembranes: Experimental Study

被引：0
|
作者：
V. V. Moroz
M. S. Bogushevich
A. M. Chernysh
E. K. Kozlova
A. S. Sharakshane
机构：
[1] Russian Academy of Medical Sciences,Institute of General Reanimatology
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 137卷
关键词：
membrane electroporation; bipolar pulses; defibrillation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied the effects of high-voltage single, double unipolar, and double bipolar electric pulses of exponential or sine shape on erythrocyte membranes. Either single or double (mono- or bipolar) pulses were used. All pulses electroporated the membranes, and the electroporation threshold did not depend on the pulse shape. Two successive pulses decreased erythrocyte number in a nonadditive way. Similar to defibrillation of the whole heart, the effect of two bipolar pulses on erythrocytes was more pronounced than the effect of two unipolar pulses.
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页码：120 / 123
页数：3
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