Adaptive immune responses in acute and chronic hepatitis C virus infection

被引：0
|
作者：
David G. Bowen
Christopher M. Walker
机构：
[1] Center for Vaccines and Immunity,
[2] Columbus Children's Research Institute,undefined
[3] College of Medicine and Public Health,undefined
[4] Ohio State University,undefined
来源：
Nature | 2005年 / 436卷
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摘要：
The hepatitis C virus (HCV) persists in the majority of infected individuals and is a significant cause of human illness and death globally. Recent studies have yielded important insights into immunity to HCV, in particular revealing the central role of T cells in viral control and clearance. Other key features of adaptive immune responses remain obscure, including mechanisms by which T cells control HCV replication, the role of antibodies in conferring protection and how cellular and humoral immunity are subverted in persistent infection.
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页码：946 / 952
页数：6
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