Human umbilical cord blood (HUCB) cells for central nervous system repair

被引:0
|
作者
Mary B. Newman
Cyndy D. Davis
Nicole Kuzmin-Nichols
Paul R. Sanberg
机构
[1] University of South Florida,Center of Excellence for Aging and Brain Repair, Departments of Neurosurgery, Psychology, Psychiatry, Neurology, Pathology and Pharmacology
[2] College of Medicine,undefined
[3] Saneron CCEL Therapeutics,undefined
[4] Inc.,undefined
来源
Neurotoxicity Research | 2003年 / 5卷
关键词
Human umbilical cord blood; Neural cell transplantation; Central nervous system; Hematopoietic cells; Stem cells;
D O I
暂无
中图分类号
学科分类号
摘要
Cellular therapy is a compelling and potential treatment for certain neurological and neurodegenerative diseases as well as a viable treatment for acute injury to the spinal cord and brain. The hematopoietic system offers alternative sources for stem cells compared to those of fetal or embryonic origin. Bone marrow stromal and umbilical cord cells have been used in pre-clinical models of brain injury, directed to differentiate into neural phenotypes, and have been related to functional recovery after engraftment in central nervous system (CNS) injury models. This paper reviews the advantages, utilization and progress of human umbilical cord blood (HUCB) cells in the neural cell transplantation and repair field.
引用
收藏
页码:355 / 368
页数:13
相关论文
共 50 条
  • [1] Human umbilical cord blood (HUCB) cells for central nervous system repair
    Newman, MB
    Davis, CD
    Kuzmin-Nichols, N
    Sanberg, PR
    [J]. NEUROTOXICITY RESEARCH, 2003, 5 (05) : 355 - 368
  • [2] Use of human umbilical cord blood (HUCB) cells to repair the damaged brain
    Newman, MB
    Emerich, DF
    Borlongan, CV
    Sanberg, CD
    Sanberg, PR
    [J]. CURRENT NEUROVASCULAR RESEARCH, 2004, 1 (03) : 269 - 281
  • [3] Applications of Human Umbilical Cord Blood Cells in Central Nervous System Regeneration
    Herranz, Antonio S.
    Gonzalo-Gobernado, Rafael
    Reimers, Diana
    Asensio, Maria J.
    Rodriguez-Serrano, Macarena
    Bazan, Eulalia
    [J]. CURRENT STEM CELL RESEARCH & THERAPY, 2010, 5 (01) : 17 - 22
  • [4] Does Intravenous Human Umbilical Cord Blood (HUCB) Cell Administration Induce Central Nervous System Tolerance to Hippocampal Transplants?
    Willing, A. E.
    Newcomb, J.
    Gemma, C.
    Sanberg, P. R.
    Bickford, P. C.
    [J]. CELL TRANSPLANTATION, 2014, 23 (06) : 789 - 789
  • [5] Cytokines produced by cultured human umbilical cord blood (HUCB) cells: Implications for brain repair
    Newman, Mary B.
    Willing, Alison E.
    Manresa, John J.
    Sanberg, Cyndy Davis
    Sanberg, Paul R.
    [J]. EXPERIMENTAL NEUROLOGY, 2006, 199 (01) : 201 - 208
  • [6] The Jerusalem human umbilical cord blood (HUCB) program
    Varadi, G
    Brautbar, C
    Elchalal, U
    Cohen, P
    Nagler, A
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1998, 102 (01) : 326 - 326
  • [7] MOLECULAR CHARACTERIZATION ON HUMAN UMBILICAL CORD BLOOD (HUCB) DERIVED STEM CELLS
    Yang, A.
    Liao, Y.
    Baxi, L.
    Ayello, J.
    van de Ven, C.
    Mitchell, K.
    Cairo, M.
    [J]. EXPERIMENTAL HEMATOLOGY, 2010, 38 (09) : S74 - S74
  • [8] ANALYSIS OF HUMAN UMBILICAL-CORD BLOOD (HUCB) FOR TRANSPLANTATION
    HARRIS, D
    LOCASCIO, J
    BESENCON, F
    RYCHLIK, S
    KIEFER, J
    YEOMAN, H
    OLSON, G
    DELUCA, D
    BARD, J
    BOYSE, E
    [J]. FASEB JOURNAL, 1992, 6 (05): : A2009 - A2009
  • [9] HUMAN UMBILICAL CORD BLOOD (HUCB) DERIVED STEM CELLS ENHANCES WOUND HEALING
    Liao, Y.
    Itoh, M.
    Roberts, S.
    Highet, A. M.
    Yang, A.
    Christiano, A.
    Cairo, M. S.
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (02) : S373 - S374
  • [10] Harvesting of human umbilical cord blood (HUCB) by various methods.
    Nagler, A
    Stockheim, D
    Elchalal, U
    [J]. BONE MARROW TRANSPLANTATION, 1998, 21 : S24 - S24