Towards a microfluidic H295R steroidogenesis assay—biocompatibility study and steroid detection on a thiol-ene-based chip

被引：0
|
作者：
Caroline Despicht
Cecilie H. Munkboel
Hua Nee Chou
Peter Ertl
Mario Rothbauer
Jörg P. Kutter
Bjarne Styrishave
Andreas Kretschmann
机构：
[1] University of Copenhagen,Toxicology and Drug Metabolism Group, Department of Pharmacy, Faculty of Health and Medical Sciences
[2] Vienna University of Technology,Institute of Applied Synthetic Chemistry, Institute of Chemical Technologies and Analytics, Faculty of Technical Chemistry
[3] Medical University of Vienna,Karl Chiari Lab for Orthopaedic Biology, Department of Orthopedics and Trauma Surgery
[4] Univeristy of Copenhagen,Microscale Analytical Systems, Department of Pharmacy, Faculty of Health and Medical Sciences
来源：
Analytical and Bioanalytical Chemistry | 2023年 / 415卷
关键词：
Thiol-ene; PDMS; Biocompatibility; Microfluidics; Steroidogenesis; Cell-based assay;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：5421 / 5436
页数：15
相关论文
共 27 条
  • [1] Towards a microfluidic H295R steroidogenesis assay-biocompatibility study and steroid detection on a thiol-ene-based chip
    Despicht, Caroline
    Munkboel, Cecilie H.
    Chou, Hua Nee
    Ertl, Peter
    Rothbauer, Mario
    Kutter, Jorg P.
    Styrishave, Bjarne
    Kretschmann, Andreas
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2023, 415 (22) : 5421 - 5436
  • [2] Evaluating H295R steroidogenesis assay data for robust interpretation
    Tinwell, H.
    Karmaus, A.
    Gaskell, V.
    Gomes, C.
    Grant, C.
    Holmes, T.
    Jonas, A.
    Kellum, S.
    Krueger, K.
    Malley, L.
    Melching-Kollmuss, S.
    Mercier, O.
    Pandya, H.
    Placke, T.
    Settivari, R.
    De Waen, B.
    REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2023, 143
  • [3] Comparison of H295R Based Steroidogenesis Assay and Primary Leydig Cell Steroidogenesis Assay To Identify Endocrine Disruptors.
    Kim, Tae Sung
    Kang, Il Hyun
    Jung, Ki Kyung
    Nam, Hye Seon
    Hong, Soon Keun
    Han, Soon Young
    Dong, Mi Sook
    Yoon, Hae Jung
    Kang, Tae Seok
    ENDOCRINE REVIEWS, 2010, 31 (03)
  • [4] The H295R steroidogenesis assay does not reflect ovarian steroidogenesis: implications for identification of EDCs toxic to female reproduction
    Vazakidou, P.
    Koopmans, C.
    Kuru, S.
    Li, T.
    Asimaki, K.
    Evangelista, S.
    Koekkoek, J.
    Leonards, P.
    Gadella, B.
    Damdimopoulou, P.
    van Duursen, M.
    TOXICOLOGY LETTERS, 2022, 368 : S178 - S178
  • [5] High-Throughput H295R Steroidogenesis Assay: Utility as an Alternative and a Statistical Approach to Characterize Effects on Steroidogenesis
    Haggard, Derik E.
    Karmaus, Agnes L.
    Martin, Matthew T.
    Judson, Richard S.
    Setzer, R. Woodrow
    Friedman, Katie Paul
    TOXICOLOGICAL SCIENCES, 2018, 162 (02) : 509 - 534
  • [6] Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay
    Gracia, Tannia
    Jones, Paul D.
    Higley, Eric B.
    Hilscherova, Klara
    Newsted, John L.
    Murphy, Margaret B.
    Chan, Alice K. Y.
    Zhang, Xiaowei
    Hecker, Markus
    Lam, Paul K. S.
    Wu, Rudolf S. S.
    Giesy, John P.
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2008, 15 (04) : 332 - 343
  • [7] Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay
    Tannia Gracia
    Paul D. Jones
    Eric B. Higley
    Klara Hilscherova
    John L. Newsted
    Margaret B. Murphy
    Alice K. Y. Chan
    Xiaowei Zhang
    Markus Hecker
    Paul K. S. Lam
    Rudolf S. S. Wu
    John P. Giesy
    Environmental Science and Pollution Research - International, 2008, 15 : 332 - 343
  • [8] The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study
    Hecker, Markus
    Hollert, Henner
    Cooper, Ralph
    Vinggaard, Anne Marie
    Akahori, Yumi
    Murphy, Margaret
    Nellemann, Christine
    Higley, Eric
    Newsted, John
    Laskey, John
    Buckalew, Angela
    Grund, Stefanie
    Maletz, Sibylle
    Giesy, John
    Timm, Gary
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2011, 18 (03) : 503 - 515
  • [9] The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study
    Markus Hecker
    Henner Hollert
    Ralph Cooper
    Anne Marie Vinggaard
    Yumi Akahori
    Margaret Murphy
    Christine Nellemann
    Eric Higley
    John Newsted
    John Laskey
    Angela Buckalew
    Stefanie Grund
    Sibylle Maletz
    John Giesy
    Gary Timm
    Environmental Science and Pollution Research, 2011, 18 : 503 - 515
  • [10] Perfluorinated compounds differentially affect steroidogenesis and viability in the human adrenocortical carcinoma (H295R) in vitro cell assay
    Kraugerud, Marianne
    Zimmer, Karin E.
    Ropstad, Erik
    Verhaegen, Steven
    TOXICOLOGY LETTERS, 2011, 205 (01) : 62 - 68
123