Response to trametinib treatment in progressive pediatric low-grade glioma patients

被引：0
|
作者：
Florian Selt
Cornelis M. van Tilburg
Brigitte Bison
Philipp Sievers
Inga Harting
Jonas Ecker
Kristian W. Pajtler
Felix Sahm
Annabelle Bahr
Michèle Simon
David T. W. Jones
Lennart Well
Victor-Felix Mautner
David Capper
Pablo Hernáiz Driever
Astrid Gnekow
Stefan M. Pfister
Olaf Witt
Till Milde
机构：
[1] Hopp Children’s Cancer Center (KiTZ),Clinical Cooperation Unit Pediatric Oncology
[2] German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK),KiTZ Clinical Trial Unit (ZIPO), Department of Pediatric Hematology and Oncology
[3] Heidelberg University Hospital,Institute of Diagnostic and Interventional Neuroradiology
[4] University Hospital Wuerzburg,Department of Neuropathology, Institute of Pathology
[5] Heidelberg University Hospital,Clinical Cooperation Unit Neuropathology
[6] German Consortium for Translational Cancer Research (DKTK),Department of Neuroradiology
[7] German Cancer Research Center (DKFZ),Department of Pediatric Oncology/Hematology, Charité Universitaetsmedizin Berlin, Corporate Member of Freie Universitaet Berlin
[8] Heidelberg University Hospital,Department of Diagnostic and Interventional Radiology and Nuclear Medicine
[9] Humboldt-Universitaet zu Berlin and Berlin Institute of Health,Department of Neurology
[10] University Medical Center Hamburg-Eppendorf,Department of Neuropathology, Corporate Member of Freie Universitaet Berlin
[11] University Medical Center Hamburg-Eppendorf,Swabian Children’s Cancer Center
[12] Humboldt-Universitaet Zu Berlin,Division of Pediatric Neurooncology
[13] and Berlin Institute of Health,Pediatric Glioma Research Group
[14] Charité-Universitaetsmedizin Berlin,undefined
[15] German Cancer Consortium (DKTK),undefined
[16] German Cancer Research Center (DKFZ),undefined
[17] University Hospital Augsburg,undefined
[18] German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK),undefined
[19] German Cancer Research Center (DKFZ),undefined
来源：
Journal of Neuro-Oncology | 2020年 / 149卷
关键词：
Pediatric low-grade glioma; Targeted therapy; BRAF; NF1; MAPK pathway; MEK inhibitor; Trametinib;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：499 / 510
页数：11
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