Long-term incidence of serious fall-related injuries after bariatric surgery in Swedish obese subjects

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作者
Lena M. S. Carlsson
Kajsa Sjöholm
Sofie Ahlin
Peter Jacobson
Johanna C. Andersson-Assarsson
Linda Karlsson Lindahl
Cristina Maglio
Cecilia Karlsson
Stephan Hjorth
Magdalena Taube
Björn Carlsson
Per-Arne Svensson
Markku Peltonen
机构
[1] the Sahlgrenska Academy at University of Gothenburg,Institute of Medicine
[2] Catholic University of the Sacred Heart,Wallenberg Centre for molecular and translational medicine
[3] University of Gothenburg,Global Medicines Development
[4] AstraZeneca Gothenburg,CVMD Translational Medicine Unit, Early Clinical Development
[5] IMED Biotech Unit,Institute of Health and Care Sciences
[6] AstraZeneca Gothenburg,undefined
[7] the Sahlgrenska Academy at University of Gothenburg,undefined
[8] National Institute for Health and Welfare,undefined
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摘要
Obesity increases risk of falling, but the effect of bariatric surgery on fall-related injuries is unknown. The aim of this study was therefore to study the association between bariatric surgery and long-term incidence of fall-related injuries in the prospective, controlled Swedish Obese Subjects study. At inclusion, body mass index was ≥ 34 kg/m2 in men and ≥38 kg/m2 in women. The surgery per-protocol group (n = 2007) underwent gastric bypass (n = 266), banding (n = 376), or vertical banded gastroplasty (n = 1365), and controls (n = 2040) received usual care. At the time of analysis (31 December 2013), median follow-up was 19 years (maximal 26 years). Fall-related injuries requiring hospital treatment were captured using data from the Swedish National Patient Register. During follow-up, there were 617 first-time fall-related injuries in the surgery group and 513 in the control group (adjusted hazard ratio 1.21, 95% CI, 1.07–1.36; P = 0.002). The incidence differed between treatment groups (P < 0.001, log-rank test) and was higher after gastric bypass than after usual care, banding and vertical banded gastroplasty (adjusted hazard ratio 0.50–0.52, P < 0.001 for all three comparisons). In conclusion, gastric bypass surgery was associated with increased risk of serious fall-related injury requiring hospital treatment.
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页码:933 / 937
页数:4
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