Is mouse embryonic stem cell technology obsolete?

被引：0
|
作者：
William C Skarnes
机构：
[1] Wellcome Trust Genome Campus,Stem Cell Engineering, Wellcome Trust Sanger Institute
来源：
Genome Biology | / 16卷
关键词：
Embryonic Stem Cell; Homologous Recombination; Mouse Embryonic Stem Cell; Cluster Regularly Interspaced Short Palindromic Repeat; Donor Plasmid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Injection of recombinant Cas9 protein and synthetic guide RNAs into mouse zygotes has been shown to facilitate gene disruption and knock-ins using the CRISPR system. These technologies may soon displace genetic modification using embryonic stem cells.
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