Molecular structure of the rabbit α2A-adrenoceptor: a contribution to the α2A-adrenoceptor versus I1 imidazoline receptor controversy

被引：0
|
作者：
M. Brüss
H. Bönisch
M. Göthert
G. J. Molderings
机构：
[1] Universität Bonn,Institut für Pharmakologie und Toxikologie
来源：
Naunyn-Schmiedeberg's Archives of Pharmacology | 2003年 / 367卷
关键词：
α; -adrenoceptor; Rabbit; Human; Imidazoline receptor rilmenidine; Central antihypertensives;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In view of the high structural and pharmacological similarities between the α2A-adrenoceptors of humans and other mammalian species, it has been concluded, in particular, from experiments in rabbits that the 2A-adrenoceptor is the exclusive site of action of central antihypertensive drugs, although the amino acid sequence of the α2A-adrenoceptor of just this species was unknown. Therefore, the aim of the present investigation was to determine the complete nucleotide sequence of the coding region of the rabbit α2A-adrenoceptor gene.
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页码：328 / 331
页数：3
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