Chronic H3R activation reduces L-Dopa-induced dyskinesia, normalizes cortical GABA and glutamate levels, and increases striatal dopamine D1R mRNA expression in 6-hydroxydopamine-lesioned male rats

被引：0
|
作者：
Alberto Avila-Luna
Arturo Gálvez-Rosas
Alexander Aguirre-Pérez
Alberto Hidalgo-Bravo
Alfonso Alfaro-Rodriguez
Camilo Ríos
José-Antonio Arias-Montaño
Antonio Bueno-Nava
机构：
[1] Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra,Coordinación de Neurociencias Básicas
[2] SSa,Laboratorio de Neurofisiología Química de la Discapacidad, Coordinación de Neurociencias Básicas
[3] Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra,Departamento de Medicina Genómica
[4] SSa,Departamento de Neuroquímica
[5] Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra,Laboratorio de Neurofarmacología Molecular, Departamento de Sistemas Biológicos
[6] SSa,Departamento de Fisiología, Biofísica y Neurociencias
[7] Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez,undefined
[8] SSa,undefined
[9] Universidad Autónoma Metropolitana,undefined
[10] Unidad Xochimilco,undefined
[11] Centro de Investigación y de Estudios Avanzados del IPN,undefined
来源：
Psychopharmacology | 2023年 / 240卷
关键词：
Dopamine; Histamine; D; receptor; H; receptor; L-Dopa-induced dyskinesias; Striatum; Cerebral cortex; Parkinson’s disease; GABA; Glutamate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1221 / 1234
页数：13
相关论文
共 14 条
  • [1] Chronic H3R activation reduces L-Dopa-induced dyskinesia, normalizes cortical GABA and glutamate levels, and increases striatal dopamine D1R mRNA expression in 6-hydroxydopamine-lesioned male rats
    Avila-Luna, Alberto
    Galvez-Rosas, Arturo
    Aguirre-Perez, Alexander
    Hidalgo-Bravo, Alberto
    Alfaro-Rodriguez, Alfonso
    Rios, Camilo
    Arias-Montano, Jose-Antonio
    Bueno-Nava, Antonio
    [J]. PSYCHOPHARMACOLOGY, 2023, 240 (06) : 1221 - 1234
  • [2] The α2 adrenoceptor antagonist idazoxan alleviates l-DOPA-induced dyskinesia by reduction of striatal dopamine levels: an in vivo microdialysis study in 6-hydroxydopamine-lesioned rats
    Buck, Kerstin
    Voehringer, Patrizia
    Ferger, Boris
    [J]. JOURNAL OF NEUROCHEMISTRY, 2010, 112 (02) : 444 - 452
  • [3] Chronic L-DOPA treatment increases striatal cannabinoid CB1 receptor mRNA expression in 6-hydroxydopamine-lesioned rats
    Zeng, BY
    Dass, B
    Owen, A
    Rose, S
    Cannizzaro, C
    Tel, BC
    Jenner, P
    [J]. NEUROSCIENCE LETTERS, 1999, 276 (02) : 71 - 74
  • [4] Targeting the D1-N-methyl-D-aspartate receptor complex reduces L-dopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson's rats
    Song, Lu
    Zhang, Zhanzhao
    Hu, Rongguo
    Cheng, Jie
    Li, Lin
    Fan, Qinyi
    Wu, Na
    Gan, Jing
    Zhou, Mingzhu
    Liu, Zhenguo
    [J]. DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 10 : 547 - 555
  • [5] The abnormal activation of D1R/Shp-2 complex involved in levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson's rats
    Wu, Na
    Wan, Ying
    Song, Lu
    Qi, Chen
    Liu, Zhenguo
    Gan, Jing
    [J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2018, 14 : 1779 - 1786
  • [6] Chronic administration of the histamine H3 receptor agonist immepip decreases l-Dopa-induced dyskinesias in 6-hydroxydopamine-lesioned rats
    Avila-Luna, Alberto
    Rios, Camilo
    Galvez-Rosas, Arturo
    Montes, Sergio
    Arias-Montano, Jose-Antonio
    Bueno-Nava, Antonio
    [J]. PSYCHOPHARMACOLOGY, 2019, 236 (06) : 1937 - 1948
  • [7] Chronic administration of the histamine H3 receptor agonist immepip decreases l-Dopa-induced dyskinesias in 6-hydroxydopamine-lesioned rats
    Alberto Avila-Luna
    Camilo Ríos
    Arturo Gálvez-Rosas
    Sergio Montes
    José-Antonio Arias-Montaño
    Antonio Bueno-Nava
    [J]. Psychopharmacology, 2019, 236 : 1937 - 1948
  • [8] Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats
    Thomsen, Mikael
    Stoica, Anca
    Christensen, Kenneth Vielsted
    Fryland, Tue
    Mikkelsen, Jens D.
    Hansen, John Bondo
    [J]. EXPERIMENTAL NEUROLOGY, 2022, 358
  • [9] LOSS OF GLUTAMIC ACID DECARBOXYLASE (Gad67) IN STRIATAL NEURONS EXPRESSING THE Drdr1a DOPAMINE RECEPTOR PREVENTS L-DOPA-INDUCED DYSKINESIA IN 6-HYDROXYDOPAMINE-LESIONED MICE
    Zhang, K.
    Chammas, C.
    Soghomonian, J. -J.
    [J]. NEUROSCIENCE, 2015, 303 : 586 - 594
  • [10] METABOTROPIC GLUTAMATE mGluR5 RECEPTOR BLOCKADE OPPOSES ABNORMAL INVOLUNTARY MOVEMENTS AND THE INCREASES IN GLUTAMIC ACID DECARBOXYLASE mRNA LEVELS INDUCED BY I-DOPA IN STRIATAL NEURONS OF 6-HYDROXYDOPAMINE-LESIONED RATS
    Yamamoto, N.
    Soghomonian, J. -J.
    [J]. NEUROSCIENCE, 2009, 163 (04) : 1171 - 1180
12