Evaluation of the biosafety of cyanoacrylate adhesive in vitro

被引：0
|
作者：
Belova M.S. [1 ]
Korovina D.G. [2 ]
Tsygankov V.N. [1 ]
Varava A.B. [1 ]
Savchenkova I.P. [2 ]
Legon’kova O.A. [1 ]
机构：
[1] Vishnevskii Institute of Surgery, Ministry of Health of Russia, Moscow
[2] Kovalenko All-Russian Scientific Research Institute of Experimental Veterinary Sciences, Moscow
来源：
Polymer Science, Series D | 2017年 / 10卷 / 4期
关键词：
biosafety; cell culture; cyanoacrylate adhesive; iodolipol (lipiodol); multipotent human mesenchymal stem cells; n-butyl-2-cyanoacrylate; regeneration; viability;
D O I：
10.1134/S1995421217040049
中图分类号：
学科分类号：
摘要：
This paper considers the evaluation of the biosafety of cyanoacrylate adhesive in vitro on human multipotent mesenchymal stem cells. This adhesive is intended for medical use, in particular, for X-ray and endovascular interventions. A toxicity study was carried out in a culture of multipotent mesenchymal stem cells isolated from human subcutaneous fat. As a result of the work, the concentration of cyanoacrylate adhesive in lipiodol was chosen, which has the lowest toxicity. © 2017, Pleiades Publishing, Ltd.
引用
收藏
页码：357 / 360
页数：3
相关论文
共 50 条
  • [1] Cyanoacrylate tissue adhesive as a membrane in socket preservation: In vitro cytotoxicity and clinical evaluation
    Mendoza-Azpur, G.
    Ortiz, J.
    Valdivia, E.
    De Souza, G.
    Collares, F.
    Meza, J.
    Shibli, J. A.
    JOURNAL OF OSSEOINTEGRATION, 2021, 13 (04) : 220 - 226
  • [2] Shear Bond Strength Evaluation of a Cyanoacrylate Orthodontic Adhesive
    Kayalioglu, Mustafa
    Uzdil, Fakir
    Kendi, Egemen
    Toroglu, Serdar
    Uzel, Ilter
    TURKISH JOURNAL OF ORTHODONTICS, 2007, 20 (02) : 102 - 109
  • [3] Evaluation of an absorbable cyanoacrylate adhesive as a suture line sealant
    Ellman, PI
    Reece, TB
    Maxey, TS
    Tache-Leon, C
    Taylor, JL
    Spinosa, DJ
    Pineros-Fernandez, AC
    Rodeheaver, GT
    Kern, JA
    JOURNAL OF SURGICAL RESEARCH, 2005, 125 (02) : 161 - 167
  • [4] CYANOACRYLATE ADHESIVE AND HEMOSTASIS
    MATSUMOTO, T
    HARDAWAY, RM
    HEISTERKAMP, CA
    PANI, KC
    LEONARD, F
    MARGETIS, PM
    ARCHIVES OF SURGERY, 1967, 94 (06) : 858 - +
  • [5] Cyanoacrylate tissue adhesive
    Wiwanitkit, Viroj
    INDIAN JOURNAL OF OPHTHALMOLOGY, 2010, 58 (04)
  • [6] CYANOACRYLATE MONOMERS AS AN ADHESIVE
    DELLEVIGNE, W
    WOLFERTH, CC
    JONES, N
    MATSUMOTO, T
    ARCHIVES OF SURGERY, 1971, 102 (05) : 493 - +
  • [7] CYANOACRYLATE ADHESIVE APPLICATION
    MATHERS, WD
    OPHTHALMIC SURGERY AND LASERS, 1987, 18 (11): : 851 - 851
  • [8] CYANOACRYLATE TISSUE ADHESIVE
    BURCHETT, N
    ARCHIVES OF EMERGENCY MEDICINE, 1991, 8 (02): : 155 - 156
  • [9] Evaluation of n-Butyl Cyanoacrylate Adhesive in Rat Subcutaneous Tissue
    Mestieri, Leticia Boldrin
    Saska, Sybele
    Carrodeguas, Raul Garcia
    Minarelli Gaspar, Ana Maria
    DERMATOLOGIC SURGERY, 2012, 38 (05) : 767 - 771
  • [10] ISOBUTYL CYANOACRYLATE AS A SKIN ADHESIVE
    HALE, JE
    POSTGRADUATE MEDICAL JOURNAL, 1970, 46 (537) : 447 - +
12345