Biologic actions and therapeutic potential of the proglucagon-derived peptides

被引：0
|
作者：
Daniel J Drucker
机构：
[1] the Director of the Banting and Best Diabetes Centre,
[2] a Staff Physician at the Toronto General Hospital,undefined
[3] and a Professor of Medicine at the University of Toronto,undefined
来源：
Nature Clinical Practice Endocrinology & Metabolism | 2005年 / 1卷
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摘要：
Proglucagon-derived peptides from the pancreas and gut regulate various aspects of energy homeostasis, with many potential therapeutic applications—glucagon is used to treat hypoglycemia, and researchers are testing glucagon antagonists and glucagon-derived peptide 1 receptor (GLP-1R) agonists to treat type 2 diabetes, and a GLP-2 analogue to treat short-bowel syndrome.
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页码：22 / 31
页数：9
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