Microwave assisted Wolff rearrangement: A facile method for the synthesis of Fmoc-β-amino acids

被引：0
|
作者：
Basanagoud S. Patil
Ganga-Ramu Vasanthakumar
Vommina V. Suresh Babu
机构：
[1] Bangalore University,Department of Studies in Chemistry, Central College Campus
来源：
Letters in Peptide Science | 2002年 / 9卷
关键词：
β-amino acids; microwave irradiation; -Fmoc-α-aminodiazoketones; Wolff rearrangement;
D O I：
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学科分类号：
摘要：
The Wolff rearrangement of α-diazoketones, derived from Fmoc-α-amino acids, under no base conditions on exposure to microwave irradiation for 40 to 60 sec to Fmoc-β-amino acids with retention of configuration in good yield (91–95%) is described.
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页码：231 / 233
页数：2
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