In-vivo intratissue ablation by nanojoule near-infrared femtosecond laser pulses

被引：0
|
作者：
Bao-Gui Wang
Iris Riemann
Harald Schubert
Karl-Juergen Halbhuber
Karsten Koenig
机构：
[1] University of Jena,Institute of Microscopic Anatomy (Anatomy II)
[2] Fraunhofer Institute of Biomedical Technology (IBMT),Institute of Laboratory Animals Science
[3] University of Jena,Faculty of Physics and Mechatronics
[4] Saarland University,undefined
[5] JenLab,undefined
来源：
Cell and Tissue Research | 2007年 / 328卷
关键词：
Ablation; Eye surgery; Myofibroblasts; Femtosecond laser; Nanoprocessing; Rabbit (New Zealand Albino);
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Non-invasive intratissue ablation was performed in the cornea of living rabbits by using 80 MHz near-infrared intense nanojoule femtosecond laser pulses. The intratissue surgical effect was induced by multiphoton absorption at a wavelength of 800 nm and was ascertained by histological examination. Highly precise intratissue ablation was obtained with no detrimental effects to the overlying or underlying layers. Activated keratocytes in the laser-treated corneas were detected with two-photon imaging postoperatively. Intratissue femtosecond laser ablation thus has potential as a effective technique in refractive surgery for the treatment of visual disorders.
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页码：515 / 520
页数：5
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