292 A Genome-Wide Association Study of Spontaneous Preterm Delivery

被引：0

作者：

H Boyd

B Feenstra

F Geller

E Feingold

K Ryckman

J Shaffer

C Laurie

Q Zhang

K Doheny

E Pugh

T Manolio

M Marazita

M Melbye

J Murray

Geneva Consortium

机构：

[1] Epidemiology Research,

[2] Statens Serum Institut,undefined

[3] Human Genetics,undefined

[4] University of Pittsburgh,undefined

[5] Pediatrics,undefined

[6] University of Iowa,undefined

[7] Biostatistics,undefined

[8] University of Washington,undefined

[9] Institute of Genetic Medicine,undefined

[10] Johns Hopkins University,undefined

[11] National Human Genome Research Institute,undefined

[12] NIH,undefined

来源：

Pediatric Research | 2010年 / 68卷

关键词：

D O I：

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学科分类号：

摘要：

Background and aims: Up to 40% of preterm deliveries (PTDs) may have a genetic component. PTD inheritance patterns are consistent with maternal genotype effects, fetal genotype effects via maternally-derived alleles, or both. However, while many candidate genes have been proposed, no common genetic variant has yet been confirmed as contributing to PTD. A genome-wide association study (GWAS) of PTD has never before been undertaken. Consequently, our objective was to examine maternal and fetal genetic contributions to spontaneous PTD in a GWAS.

引用

页码：150 / 150

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