Trans-platinum(II) complexes with cyclohexylamine as expectator ligand induce necrosis in tumour cells by inhibiting DNA synthesis and RNA transcription

被引：0
|
作者：
V. Cepero
B. García-Serrelde
V. Moneo
F. Blanco
A. M. González-Vadillo
A. Álvarez-Valdés
C. Navarro-Ranninger
A. Carnero
机构：
[1] Centro Nacional de Investigaciones Oncológicas (CNIO),Programa de Terapias Experimentales
[2] Universidad Autónoma de Madrid,Departamento de Química Inorgánica
来源：
Clinical and Translational Oncology | 2007年 / 9卷
关键词：
Antitumour drugs; Platinum anticancer drugs; platin; Cytotoxic activity; Cell cycle;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：521 / 530
页数：9
相关论文
共 42 条
  • [1] Trans-platinum(II) complexes with cyclohexylamine as expectator ligand induce necrosis in tumour cells by inhibiting DNA synthesis and RNA transcription
    Cepero, V.
    Garcia-Serrelde, B.
    Moneo, V.
    Blanco, F.
    Gonzalez-Vadillo, A. M.
    Alvarez-Valdes, A.
    Navarro-Ranninger, C.
    Carnero, A.
    CLINICAL & TRANSLATIONAL ONCOLOGY, 2007, 9 (08): : 521 - 530
  • [2] INVITRO EFFECTS OF CIS AND TRANS-PLATINUM COMPLEXES ON RNA AND DNA-SYNTHESIS
    KOHL, HH
    MILLER, D
    MCAULIFFE, CA
    FRIEDMAN, ME
    FEDERATION PROCEEDINGS, 1983, 42 (07) : 2005 - 2005
  • [3] EFFECTS OF CIS-PLATINUM AND TRANS-PLATINUM COMPLEXES ON RNA-TRANSCRIPTION
    MILLER, D
    MINAHAN, DMA
    FRIEDMAN, ME
    KOHL, HH
    MCAULIFFE, CA
    CHEMICO-BIOLOGICAL INTERACTIONS, 1983, 44 (03) : 311 - 316
  • [4] SYNTHESIS OF TRANS-PLATINUM(II) COMPLEXES BY PHOTOCHEMICAL ISOMERIZATION
    MASTIN, SH
    HAAKE, P
    JOURNAL OF THE CHEMICAL SOCIETY D-CHEMICAL COMMUNICATIONS, 1970, (04): : 202 - &
  • [5] Synthesis, characterization and biological activity of trans-platinum(II) and trans-platinum(IV) complexes with 4-hydroxymethylpyridine
    Martínez, A
    Lorenzo, J
    Prieto, MJ
    de Llorens, R
    Font-Bardia, M
    Solans, X
    Avilés, FX
    Moreno, V
    CHEMBIOCHEM, 2005, 6 (11) : 2068 - 2077
  • [6] Synthesis, characterization and biological activity of trans-platinum(II) complexes with chloroquine
    Navarro, Maribel
    Castro, William
    Higuera-Padilla, Angel R.
    Sierraalta, Anibal
    Jesus Abad, Maria
    Taylor, Peter
    Sanchez-Delgado, Roberto A.
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2011, 105 (12) : 1684 - 1691
  • [7] Antiproliferative activity of some cis-/trans-platinum(II) complexes on HeLa cells
    Arandjelovic, S
    Tesic, Z
    Juranic, Z
    Radulovic, S
    Vrvic, M
    Potkonjak, B
    Ilic, Z
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2002, 21 (04) : 519 - 526
  • [8] Synthesis, cytotoxicity, and DNA-binding levels of ammine/cyclohexylamine platinum(II) complexes with dicarboxylates
    Zhang, JC
    Yong, S
    SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2006, 36 (04) : 345 - 351
  • [9] trans-Platinum(II) Thionate Complexes: Synthesis, Structural Characterization, and in vitro Biological Assessment as Potent Anticancer Agents
    Sakamaki, Yoshie
    Mirsadeghi, Hasti Ahmadi
    Fereidoonnezhad, Masood
    Mirzaei, Faezeh
    Dehkordi, Zahra Moghimi
    Chamyani, Samira
    Alshami, Mia
    Abedanzadeh, Sedigheh
    Shahsavari, Hamid R.
    Beyzavi, M. Hassan
    CHEMPLUSCHEM, 2019, 84 (10): : 1525 - 1535
  • [10] Structure-activity relationship of new trans-platinum(II) and (IV) complexes with cyclohexylamine.: Interference with cell cycle progression and induction of cell death
    Gonzalez-Vadillo, Ana M.
    Alvarez-Valdes, Amparo
    Moneo, Victoria
    Blanco, Fernando
    Diaz, Raquel G.
    Carnero, Amancio
    Navarro-Ranninger, Carmen
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2007, 101 (04) : 551 - 558
12345