The effects of metformin on gut microbiota and the immune system as research frontiers

被引：0
|
作者：
Michael Pollak
机构：
[1] McGill University,Division of Cancer Prevention, Department of Oncology
来源：
Diabetologia | 2017年 / 60卷
关键词：
Diabetes; Metformin; Microbiome; Microbiota immunity cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Recent studies have revealed that metformin influences gut microbiota and the immune system although neither is a classic target of the drug. This research has revealed complexity not previously appreciated, and opened new research directions. The extent to which immunomodulatory effects and actions on the microbiota are related to each other and account for effects on host energy metabolism remains to be determined. These sites of action may be relevant not only to the efficacy of metformin for its established use in type 2 diabetes, but also to proposed novel indications in oncology and other diseases.
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页码：1662 / 1667
页数：5
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