Molecular characterization of clinical carbapenem-resistant Enterobacterales from Qatar

被引：0

作者：

Fatma Ben Abid

Clement K. M. Tsui

Yohei Doi

Anand Deshmukh

Christi L. McElheny

William C. Bachman

Erin L. Fowler

Ahmed Albishawi

Kamran Mushtaq

Emad B. Ibrahim

Sanjay H. Doiphode

Manal M. Hamed

Muna A. Almaslmani

Abdullatif Alkhal

Adeel A. Butt

Ali S. Omrani

机构：

[1] Hamad Medical Corporation,Division of Infectious Diseases, Department of Medicine

[2] Hamad Medical Corporation,Communicable Diseases Center

[3] Weill Cornell Medicine-Qatar,Department of Pathology

[4] Sidra Medicine,Division of Infectious Diseases, Faculty of Medicine

[5] University of British Columbia,Division of Infectious Diseases

[6] University of Pittsburgh School of Medicine,Departments of Microbiology and Infectious Diseases

[7] Fujita Health University School of Medicine,Division of Microbiology, Department of Pathology and Laboratory Medicine

[8] Hamad Medical Corporation,Department of Medicine

[9] Hamad Medical Corporation,Clinical Epidemiology Research Unit

[10] Hamad Medical Corporation,undefined

来源：

European Journal of Clinical Microbiology & Infectious Diseases | 2021年 / 40卷

关键词：

CRE; Carbapenemase; KPC; NDM; VIM; OXA; Enterobacterales; Qatar; Middle East;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

One hundred forty-nine carbapenem-resistant Enterobacterales from clinical samples obtained between April 2014 and November 2017 were subjected to whole genome sequencing and multi-locus sequence typing. Klebsiella pneumoniae (81, 54.4%) and Escherichia coli (38, 25.5%) were the most common species. Genes encoding metallo-β-lactamases were detected in 68 (45.8%) isolates, and OXA-48-like enzymes in 60 (40.3%). blaNDM-1 (45; 30.2%) and blaOXA-48 (29; 19.5%) were the most frequent. KPC-encoding genes were identified in 5 (3.6%) isolates. Most common sequence types were E. coli ST410 (8; 21.1%) and ST38 (7; 18.4%), and K. pneumoniae ST147 (13; 16%) and ST231 (7; 8.6%).

引用

页码：1779 / 1785

页数：6

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