Stress response in tumor-infiltrating T cells is linked to immunotherapy resistance

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Nature Medicine | 2023年 / 29卷
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A newly composed single-cell transcriptomic atlas of tumor-infiltrating T cells across 16 cancer types revealed previously undescribed T cell states and heterogeneity. A unique T cell stress response state, TSTR, was linked to immunotherapy resistance. Our high-resolution T cell reference maps, web portal, and annotation tool can assist efforts to develop T cell therapies.
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页码：1336 / 1337
页数：1
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