Botulinum toxin: evidence-based medicine criteria in blepharospasm and hemifacial spasm

被引：2
|
作者：
Wolfgang H. Jost
André Kohl
机构：
[1] Department of Neurology,
[2] and Clinical Neurophysiology,undefined
[3] Deutsche Klinik für Diagnostik,undefined
[4] Aukammallee 33,undefined
[5] 65191 Wiesbaden,undefined
[6] Germany,undefined
[7] Tel.: ++49-611-577321,undefined
[8] Fax: ++49-611-577311,undefined
[9] e-mail: jost@botulinumtoxin.de,undefined
来源：
Journal of Neurology | 2001年 / 248卷 / Suppl 1期
关键词：
Key words Botulinum toxin; Hemifacial spasm; Blepharospasm; Evidence-based medicine;
D O I：
10.1007/PL00007813
中图分类号：
学科分类号：
摘要：
Botulinum A toxin is recognized and approved for symptomatic treatment of hemifacial spasm and blepharospasm. The state of trials is good, although double-blind placebo-controlled studies have been carried out involving only a small number of cases. Open case control studies have been done with large patient collectives. In both indications, treatment with botulinum toxin reaches the highest EBM degree in a critical evaluation.
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页码：I21 / I24
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