Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer

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作者
Graeme P. Young
Erin L. Symonds
Hans Jørgen Nielsen
Linnea Ferm
Ib J. Christensen
Evelien Dekker
Manon van der Vlugt
Rosalie C. Mallant-Hent
Nicky Boulter
Betty Yu
Michelle Chan
Gregor Tevz
Lawrence C. LaPointe
Susanne K. Pedersen
机构
[1] Flinders University,Flinders Health and Medical Research Institute
[2] Flinders Medical Centre,Bowel Health Service
[3] University of Copenhagen,Department of Surgical Gastroenterology, Hvidovre Hospital
[4] Amsterdam University Medical Centers,Department of Gastroenterology and Hepatology
[5] Flevo Hospital,Department of Gastroenterology
[6] Clinical Genomics Pty Ltd,undefined
[7] Clinical Genomics Technologies Ltd,undefined
来源
Clinical Epigenetics | 2021年 / 13卷
关键词
Methylated circulating tumor DNA; Colorectal cancer screening;
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  • [1] Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer
    Young, Graeme P.
    Symonds, Erin L.
    Nielsen, Hans Jorgen
    Ferm, Linnea
    Christensen, Ib J.
    Dekker, Evelien
    van der Vlugt, Manon
    Mallant-Hent, Rosalie C.
    Boulter, Nicky
    Yu, Betty
    Chan, Michelle
    Tevz, Gregor
    LaPointe, Lawrence C.
    Pedersen, Susanne K.
    [J]. CLINICAL EPIGENETICS, 2021, 13 (01)
  • [2] Concordance of the methylated ctDNA biomarkers IRF4, BCAT1 and IKZF1 as a screening test for colorectal cancer
    Young, Graeme
    Pedersen, Susanne
    Boulter, Nicky
    Tevz, Gregor
    Yu, Betty
    Chan, Michelle
    Nielsen, Hans J.
    Firm, Lin-Nea
    Christensen, J.
    Dek-Ker, Evelien
    Symonds, Erin L.
    [J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2019, 34 : 50 - 50
  • [3] Detection of methylated BCAT1 and IKZF1 in circulating tumor DNA is specific for colorectal cancer but not for breast or prostate cancer
    Winter, J.
    Sheehan-Hennessy, L.
    Pedersen, S.
    Wassie, M.
    Eaton, M.
    Chong, M.
    Young, G.
    Symonds, E.
    [J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2021, 36 : 14 - 14
  • [4] Methylated BCAT1/IKZF1 DNA: a breakthrough in colorectal cancer diagnosis?
    Bhattarai, Abhinav
    Shah, Sangam
    Khadka, Priyatam
    Abu Serhan, Hashem
    Sah, Ranjit
    Sah, Sanjit
    [J]. ANNALS OF MEDICINE AND SURGERY, 2024, 86 (01): : 11 - 12
  • [5] Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia
    Susanne K. Pedersen
    Erin L. Symonds
    Rohan T. Baker
    David H. Murray
    Aidan McEvoy
    Sascha C. Van Doorn
    Marco W. Mundt
    Stephen R. Cole
    Geetha Gopalsamy
    Dileep Mangira
    Lawrence C. LaPointe
    Evelien Dekker
    Graeme P. Young
    [J]. BMC Cancer, 15
  • [6] Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia
    Pedersen, Susanne K.
    Symonds, Erin L.
    Baker, Rohan T.
    Murray, David H.
    McEvoy, Aidan
    Van Doorn, Sascha C.
    Mundt, Marco W.
    Cole, Stephen R.
    Gopalsamy, Geetha
    Mangira, Dileep
    LaPointe, Lawrence C.
    Dekker, Evelien
    Young, Graeme P.
    [J]. BMC CANCER, 2015, 15 : 1
  • [7] Comparison of a methylated BCAT1/IKZF1 blood test with CEA for recurrent colorectal cancer
    Young, G.
    Mansfield, S.
    Pedersen, S.
    Murray, D.
    Baker, R.
    Hollington, P.
    Rabbitt, P.
    Symonds, E. L.
    [J]. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2016, 31 : 63 - 64
  • [8] Methylated BCAT1 and IKZF1 DNA in Plasma As Novel Biomarkers for Colorectal Cancer Recurrence
    Symonds, Erin L.
    Mansfield, Scott
    Mangira, Dileep
    Murray, David
    Baker, Rohan T.
    Pedersen, Susanne K.
    LaPointe, Lawrence C.
    Young, Graeme P.
    [J]. GASTROENTEROLOGY, 2015, 148 (04) : S364 - S364
  • [9] Evaluation of a 2-Gene (IKZF1 and BCAT1) DNA Blood Test for Detection of Colorectal Cancer
    Young, Graeme P.
    Pedersen, Susanne K.
    Dekker, Evelien
    Cole, Stephen R.
    Osborne, Joanne M.
    Symonds, Erin L.
    Mallant-Hent, Rosalie C.
    McEvoy, Aidan
    Baker, Rohan
    Gaur, Snigdha
    Murray, David H.
    LaPointe, Lawrence C.
    [J]. GASTROENTEROLOGY, 2014, 146 (05) : S56 - S57
  • [10] Methylated BCAT1 and IKZF1 DNA in tissue and plasma from colorectal cancer cases.
    Symonds, Erin L.
    Baker, Rohan
    Bastin, Dawn
    Bambacas, Libby
    Byrne, Susan
    Young, Graeme P.
    Pedersen, Susanne Kartin
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (04)