Radiochemical separation of no-carrier-added 186Re from proton irradiated tungsten target

被引：0
|
作者：
Ramu Ram
Rubel Chakravarty
Sachin Jadhav
Sudipta Chakraborty
K. C. Jagadeesan
S. V. Thakare
Ashutosh Dash
机构：
[1] Bhabha Atomic Research Centre,Radiopharmaceuticals Division
[2] Homi Bhabha National Institute,undefined
来源：
Journal of Radioanalytical and Nuclear Chemistry | 2020年 / 325卷
关键词：
Re; MEK; Mesoporous alumina; No-carrier-added; Radiochemical separation; Radiopharmaceuticals;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Rhenium-186 [t½ = 3.7 d, 1.07 MeV β−-particles, 137 keV γ-ray] is an emerging radioisotope which holds tremendous potential in preparation of theranostic radiopharmaceuticals. This radioisotope was produced in a no-carrier-added form by irradiation of enriched 186W target via 186W(p, n) 186Re reaction in a pelletron. A facile radiochemical separation procedure based on selective solvent extraction in methylethyl ketone medium followed by column chromatography using mesoporous alumina sorbent has been developed to obtain 186Re in a form suitable for radiopharmaceutical preparation. This approach is expected to promote widespread utilization of this radioisotope for the benefit of cancer patients.
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页码：875 / 883
页数：8
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