X-ray structure determination using low-resolution electron microscopy maps for molecular replacement

被引：0
|
作者：
Ryan N Jackson
Airlie J McCoy
Thomas C Terwilliger
Randy J Read
Blake Wiedenheft
机构：
[1] Montana State University,Department of Microbiology and Immunology
[2] University of Cambridge,Department of Haematology
[3] Cambridge Institute for Medical Research,Bioscience Division
[4] Los Alamos National Laboratory,undefined
来源：
Nature Protocols | 2015年 / 10卷
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摘要：
Molecular replacement is often used to solve the “phase problem” in X-ray crystallography. This protocol explains how low-resolution maps generated using electron microscopy can be used for the molecular replacement step in solving X-ray structures.
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页码：1275 / 1284
页数：9
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