Polymorphism of Human Mitochondrial DNA

被引:0
|
作者
M. A. Bermisheva
T. V. Viktorova
E. K. Khusnutdinova
机构
[1] Russian Academy of Sciences,Institute of Biochemistry and Genetics
[2] Ufa,undefined
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关键词
Sequence Variation; Evolutionary History; Human Population; Large Data; Direct Sequencing;
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摘要
To date, a large data set on the mitochondrial DNA (mtDNA) sequence variation in human populations has been accumulated. The use of direct sequencing of the main noncoding region of mtDNA along with the RFLP analysis provide performance of complex analysis of mtDNA polymorphism in human populations. This approach proved to be effective for obtaining molecular genetic portraits of the world populations, as well as for the elucidation of the human evolutionary history and past migrations.
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页码:849 / 859
页数:10
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