Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis

被引:0
|
作者
Takashi Sekiya
Ikkou Kashiwagi
Rei Yoshida
Tomohiro Fukaya
Rimpei Morita
Akihiro Kimura
Hiroshi Ichinose
Daniel Metzger
Pierre Chambon
Akihiko Yoshimura
机构
[1] Keio University School of Medicine,Department of Microbiology and Immunology
[2] Graduate School of Bioscience and Biotechnology,undefined
[3] Tokyo Institute of Technology,undefined
[4] Institut de Génétique et de Biologie Moléculaire et Cellulaire,undefined
[5] Université de Strasbourg,undefined
[6] Japan Science and Technology Agency,undefined
[7] Core Research for Evolutional Science and Technology,undefined
来源
Nature Immunology | 2013年 / 14卷
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学科分类号
摘要
Sekiya and colleagues demonstrate that the Nr4a nuclear receptors, which are encoded by immediate-early genes upregulated by TCR stimulation in thymocytes, have an essential role in regulatory T cell development.
引用
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页码:230 / 237
页数:7
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