Precision gestational diabetes treatment: a systematic review and meta-analyses

被引:5
|
作者
Jamie L. Benham
Véronique Gingras
Niamh-Maire McLennan
Jasper Most
Jennifer M. Yamamoto
Catherine E. Aiken
Susan E. Ozanne
Rebecca M. Reynolds
机构
[1] Cumming School of Medicine,Department of Medicine and Community Health Sciences
[2] University of Calgary,Department of Nutrition
[3] Université de Montréal,Research Center
[4] Sainte-Justine University Hospital Center,MRC Centre for Reproductive Health
[5] Queens’s Medical Research Institute,Centre for Cardiovascular Science
[6] University of Edinburgh,Department of Orthopedics
[7] Queens’s Medical Research Institute,Internal Medicine
[8] University of Edinburgh,Department of Obstetrics and Gynaecology
[9] Zuyderland Medical Center,NIHR Cambridge Biomedical Research Centre
[10] University of Manitoba,Division of Preventative Medicine, Department of Medicine
[11] the Rosie Hospital,Department of Nutrition
[12] University of Cambridge,Novo Nordisk Foundation Center for Basic Metabolic Research
[13] University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit,Diabetes Unit, Endocrine Division
[14] Wellcome-MRC Institute of Metabolic Science,Center for Genomic Medicine
[15] Brigham and Women’s Hospital and Harvard Medical School,Department of Clinical Sciences
[16] Harvard T.H. Chan School of Public Health,Department of Molecular Genetics
[17] Faculty of Health and Medical Sciences,Division of Pediatric Endocrinology, Department of Pediatrics
[18] University of Copenhagen,Department of Clinical and Biomedical Sciences
[19] Massachusetts General Hospital,Departament de Medicina
[20] Massachusetts General Hospital,Department of Medicine
[21] Lund University Diabetes Centre,Division of Endocrinology, Diabetes and Metabolism
[22] Lund University,Department of Pediatrics
[23] Madras Diabetes Research Foundation,Herman B Wells Center for Pediatric Research
[24] Saint Louis University School of Medicine,Center for Diabetes and Metabolic Diseases
[25] SSM Health Cardinal Glennon Children’s Hospital,Department of Biostatistics and Epidemiology
[26] University of Exeter Medical School,Department of Pediatrics
[27] CIBER-BBN,Division of Population Health & Genomics, School of Medicine
[28] ISCIII,Department of Pediatrics
[29] Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU),Stanford Diabetes Research Center
[30] Universitat Autònoma de Barcelona,Department of Nutrition
[31] Program in Metabolism and Medical & Population Genetics,Institute for Molecular Medicine Finland FIMM
[32] Broad Institute,Department of Pediatrics, Division of Endocrinology
[33] Harvard Medical School,Department of Medicine
[34] Johns Hopkins University School of Medicine,Department of Medicine & Therapeutics
[35] Indiana University School of Medicine,Department of Pediatrics and Clinical Genetics
[36] Indiana University School of Medicine,Department of Medicine
[37] Indiana University School of Medicine,Centre for Cardiovascular Science, Queen’s Medical Research Institute
[38] Rutgers School of Public Health,Department of Epidemiology
[39] University Hospital Leuven,Metabolic Disease Unit
[40] Erasmus Medical Center,Department of Medicine
[41] University of Dundee,Department of Pediatrics and Medicine
[42] Stanford School of Medicine,Welch Center for Prevention, Epidemiology, and Clinical Research
[43] Stanford University,Department of Medicine
[44] Stanford School of Medicine,Department of Health Policy and Management
[45] Stanford University,Institute for Clinical Diabetology, German Diabetes Center
[46] University of Florida,Department of Medicine
[47] University of North Carolina at Chapel Hill,Department of Epidemiology
[48] Helsinki University Hospital,Mohn Center for Diabetes Precision Medicine, Department of Clinical Science
[49] Abdominal Centre/Endocrinology,Children and Youth Clinic
[50] Folkhalsan Research Center,Eastern Health Clinical School
来源
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D O I
10.1038/s43856-023-00371-0
中图分类号
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摘要
Gestational diabetes (GDM) is high blood sugar first detected during pregnancy. Normalizing blood sugar levels quickly is important to avoid pregnancy complications. Many women achieve this with lifestyle changes, such as to diet, but some need to inject insulin or take tablets. We did two thorough reviews of existing research to see if we could predict which women need medication. Firstly we looked for ways to identify the characteristics of women who benefit most from changing their lifestyles to treat GDM, but found very limited research on this topic. We secondly searched for characteristics that help identify women who need medication to treat GDM. We found some useful characteristics that are obtained during routine pregnancy care. Further studies are needed to test if additional information could provide even better information about how we could make GDM treatment more tailored for individuals during pregnancy.
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