A Convenient Synthesis of NovelDerivatives of Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5,6-dione

被引：0
|
作者：
Mosselhi A. N. Mosselhi
机构：
[1] Department of Chemistry,
[2] Faculty of Science,undefined
[3] University of Cairo,undefined
[4] Giza,undefined
[5] Egypt,undefined
来源：
Monatshefte für Chemie / Chemical Monthly | 2002年 / 133卷
关键词：
Keywords. Pyrimidines; Synthetic methods; 1,2,4-Triazolopyrimidinone; Propenoate ester; Pyrido-1,2,4-triazolo-pyrimidinedione;
D O I：
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摘要：
 Reaction of 6-Amino-2-thiouracil with hydrazonoyl halides yielded regioselectively 7-amino-1,3-disubstituted-1,2,4-triazolo[4,3-a]pyrimidine derivatives. Upon treatment with methyl (Z)-2-benzoylamino-3-dimethylaminopropenoate, the corresponding methyl (Z)-2-benzoylamino-3-([1,2, 4]triazolo[4,3-a]pyrimidin-7-yl)-amino propenoates were obtained which cyclized in the presence of sodium ethoxide to afford novel derivatives of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5,6-(1H,8H)-diones.
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页码：1297 / 1304
页数：7
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