In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

被引：0
|
作者：
Brandon J DeKosky
Takaaki Kojima
Alexa Rodin
Wissam Charab
Gregory C Ippolito
Andrew D Ellington
George Georgiou
机构：
[1] University of Texas at Austin,Department of Chemical Engineering
[2] Laboratory of Molecular Biotechnology,Department of Molecular Biosciences
[3] Graduate School of Bioagricultural Sciences,Department of Biomedical Engineering
[4] Nagoya University,undefined
[5] University of Texas at Austin,undefined
[6] Center for Systems and Synthetic Biology,undefined
[7] University of Texas at Austin,undefined
[8] Institute for Cellular and Molecular Biology,undefined
[9] University of Texas at Austin,undefined
[10] University of Texas at Austin,undefined
来源：
Nature Medicine | 2015年 / 21卷
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摘要：
Georgiou and colleagues describe a single-cell, emulsion-based approach for the high-throughput determination of the paired antibody variable heavy and light chain (VH-VL) repertoire encoded by the more than 2 × 106 B cells in human peripheral blood samples.
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页码：86 / 91
页数：5
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