Gender differences in the cardiovascular effect of sex hormones

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作者
Cristiana Vitale
Michael E. Mendelsohn
Giuseppe M. C. Rosano
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[1] Center for Clinical and Basic Research,Department of Medical Sciences
[2] IRCCS San Raffaele,undefined
[3] Molecular Cardiology Research Center,undefined
[4] Tufts Medical Center,undefined
[5] San Raffaele Sulmona,undefined
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摘要
Sex differences in vascular biology are determined not only by gender-related differences in sex steroid levels, but also by gender-specific tissue and cellular differences that mediate sex-specific responses to a variety of stimuli. This Review discusses the influence of estrogen and testosterone on the development of atherosclerosis, through direct vascular effects and via effects on cardiovascular risk.
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页码:532 / 542
页数:10
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