The complete structure of the large subunit of the mammalian mitochondrial ribosome

被引:0
|
作者
Basil J. Greber
Daniel Boehringer
Marc Leibundgut
Philipp Bieri
Alexander Leitner
Nikolaus Schmitz
Ruedi Aebersold
Nenad Ban
机构
[1] Institute of Molecular Biology and Biophysics,Department of Biology
[2] Otto-Stern-Weg 5,Department of Biology
[3] ETH Zurich,undefined
[4] CH-8093 Zurich,undefined
[5] Switzerland,undefined
[6] Institute of Molecular Systems Biology,undefined
[7] Auguste-Piccard-Hof 1,undefined
[8] ETH Zurich,undefined
[9] CH-8093 Zurich,undefined
[10] Switzerland,undefined
[11] Faculty of Science,undefined
[12] University of Zurich,undefined
[13] CH-8057 Zurich,undefined
[14] Switzerland,undefined
来源
Nature | 2014年 / 515卷
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摘要
The structure of the 39S large mitoribosome subunit is solved by cryo-electron microscopy at an impressive 3.4 Å resolution, revealing the location of 50 ribosomal proteins, the peptidyl transferase centre, the tRNAs within this active site, and the nascent peptide chain within the exit tunnel.
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页码:283 / 286
页数:3
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