DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

被引：0
|
作者：
Anne Seeboth
Daniel L. McCartney
Yunzhang Wang
Robert F. Hillary
Anna J. Stevenson
Rosie M. Walker
Archie Campbell
Kathryn L. Evans
Andrew M. McIntosh
Sara Hägg
Ian J. Deary
Riccardo E. Marioni
机构：
[1] University of Edinburgh,Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine
[2] Karolinska Institutet,Department of Medical Epidemiology and Biostatistics
[3] University of Edinburgh,Centre for Cognitive Ageing and Cognitive Epidemiology
[4] University of Edinburgh,Division of Psychiatry, Royal Edinburgh Hospital
[5] University of Edinburgh,Department of Psychology
来源：
Clinical Epigenetics | 2020年 / 12卷
关键词：
Ageing; Epigenetics; Stochastic epigenetic mutations; Epigenetic outliers; Survival; Generation Scotland; Lothian Birth Cohorts;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 15 条
  • [1] DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936
    Seeboth, Anne
    McCartney, Daniel L.
    Wang, Yunzhang
    Hillary, Robert F.
    Stevenson, Anna J.
    Walker, Rosie M.
    Campbell, Archie
    Evans, Kathryn L.
    McIntosh, Andrew M.
    Hagg, Sara
    Deary, Ian J.
    Marioni, Riccardo E.
    [J]. CLINICAL EPIGENETICS, 2020, 12 (01)
  • [2] Studying lifetime cognitive ageing in the Lothian Birth Cohorts of 1921 and 1936
    Deary, Ian J.
    Davies, Gail
    Harris, Sarah
    Luciano, Michelle
    Lopez, Lorna
    Starr, John
    [J]. JOURNAL OF AGING AND PHYSICAL ACTIVITY, 2012, 20 : S13 - S13
  • [3] Cohort Profile: The Lothian Birth Cohorts of 1921 and 1936
    Deary, Ian J.
    Gow, Alan J.
    Pattie, Alison
    Starr, John M.
    [J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2012, 41 (06) : 1576 - 1584
  • [4] Cohort Profile Update: The Lothian Birth Cohorts of 1921 and 1936
    Taylor, Adele M.
    Pattie, Alison
    Deary, Ian J.
    [J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2018, 47 (04) : 1042 - +
  • [5] Brain lesions, hypertension and cognitive ageing in the 1921 and 1936 Aberdeen birth cohorts
    Murray, Alison D.
    Staff, Roger T.
    McNeil, Chris J.
    Salarirad, Sima
    Starr, John M.
    Deary, Ian J.
    Whalley, Lawrence J.
    [J]. AGE, 2012, 34 (02): : 451 - 459
  • [6] Brain lesions, hypertension and cognitive ageing in the 1921 and 1936 Aberdeen birth cohorts
    Alison D. Murray
    Roger T. Staff
    Chris J. McNeil
    Sima Salarirad
    John M. Starr
    Ian J. Deary
    Lawrence J. Whalley
    [J]. AGE, 2012, 34 : 451 - 459
  • [7] Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921
    Harris, Sarah E.
    Marioni, Riccardo E.
    Martin-Ruiz, Carmen
    Pattie, Alison
    Gow, Alan J.
    Cox, Simon R.
    Corley, Janie
    von Zglinicki, Thomas
    Starr, John M.
    Deary, Ian J.
    [J]. MECHANISMS OF AGEING AND DEVELOPMENT, 2016, 154 : 43 - 48
  • [8] Stability and Change in Intelligence From Age 11 to Ages 70, 79, and 87: The Lothian Birth Cohorts of 1921 and 1936
    Gow, Alan J.
    Johnson, Wendy
    Pattie, Alison
    Brett, Caroline E.
    Roberts, Beverly
    Starr, John M.
    Deary, Ian J.
    [J]. PSYCHOLOGY AND AGING, 2011, 26 (01) : 232 - 240
  • [9] DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921
    Sibbett, Ruth A.
    Altschul, Drew M.
    Marioni, Riccardo E.
    Deary, Ian J.
    Starr, John M.
    Russ, Tom C.
    [J]. BMC PSYCHIATRY, 2020, 20 (01)
  • [10] DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921
    Ruth A. Sibbett
    Drew M. Altschul
    Riccardo E. Marioni
    Ian J. Deary
    John M. Starr
    Tom C. Russ
    [J]. BMC Psychiatry, 20
12