Effect of Antibodies to Glutamate on Retention of Conditioned Passive Avoidance Response in Rats with Ischemic Injury of the Prefrontal Cortex

被引：0

作者：

G. A. Romanova

F. M. Shakova

V. Yu. Gorbatov

Yu. N. Kvashennikova

T. V. Davydova

机构：

[1] Russian Academy of Medical Sciences,Institute of General Pathology and Pathophysiology

来源：

Bulletin of Experimental Biology and Medicine | 2010年 / 149卷

关键词：

photothrombosis; prefrontal cortex; learning; memory; antibodies to glutamate;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Experiments were performed on rats with bilateral photothrombosis of vessels in the prefrontal cortex. Intranasal administration of antibodies to glutamate (1 h after ischemia of the brain cortex) improved retention of conditioned passive avoidance response, which was elicited before ischemic damage. The content of antibodies to glutamate in the serum of rats increased significantly on day 8 after bilateral photochemical thrombosis of vessels in the prefrontal cortex compared to that in the control.

引用

页码：289 / 292

页数：3

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[1] Effect of Antibodies to Glutamate on Retention of Conditioned Passive Avoidance Response in Rats with Ischemic Injury of the Prefrontal Cortex
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