Discontinuation of Methotrexate Therapy in Older Patients with Newly Diagnosed Rheumatoid ArthritisAnalysis of Administrative Health Databases in Québec, Canada

被引：0
|
作者：
Sasha Bernatsky
Debbie Ehrmann Feldman
机构：
[1] McGill University,Department of Clinical Epidemiology
[2] Université de Montréal,École de Réadaptation
[3] Research Institute of the McGill University Health Centre,Division of Clinical Epidemiology
来源：
Drugs & Aging | 2008年 / 25卷
关键词：
Rheumatoid Arthritis; Methotrexate; Folic Acid; Drug Discontinuation; Methotrexate Therapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Rheumatoid arthritis (RA) is a potentially devastating form of chronic arthritis. Methotrexate is the cornerstone of drug therapy of the disorder, and may slow or prevent joint damage. Unfortunately, this agent is not without adverse effects. Furthermore, increasing age has been been invoked as a predictor of greater toxicity and drug discontinuation by some, but not all, investigators.
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页码：879 / 884
页数：5
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