A mechanism for impaired fear recognition after amygdala damage

被引:0
|
作者
Ralph Adolphs
Frederic Gosselin
Tony W. Buchanan
Daniel Tranel
Philippe Schyns
Antonio R. Damasio
机构
[1] University of Iowa,Department of Neurology
[2] California Institute of Technology,Division of Humanities and Social Sciences
[3] Université de Montréal,Departement de Psychologie
[4] University of Glasgow,Department of Psychology
来源
Nature | 2005年 / 433卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
We continuously look at people's faces to judge how they feel: happy, sad, angry or afraid? A region of the brain called the amygdala is needed to make such judgements, and a new study shows how. A rare subject with bilateral amygdala damage was impaired in her ability to make use of information from the eye region in the face. This resulted in a severe impairment in her ability to recognize fear. Strikingly, when she was instructed to look at other people's eyes, her recognition of fear became normal. This suggests that our brains actively seek out important social cues in the environment, and that impairments in this mechanism in diseases such as autism might be overcome by instructing patients to change the way they look at the world.
引用
收藏
页码:68 / 72
页数:4
相关论文
共 50 条
  • [1] A mechanism for impaired fear recognition after amygdala damage
    Adolphs, R
    Gosselin, F
    Buchanan, TW
    Tranel, D
    Schyns, P
    Damasio, AR
    [J]. NATURE, 2005, 433 (7021) : 68 - 72
  • [2] Impaired recognition of fear in a Chinese man with bilateral cingulate and unilateral amygdala damage
    Wang, K
    Hoosain, R
    Li, XS
    Zhou, JN
    Wang, CQ
    Fu, XM
    Yue, XM
    [J]. COGNITIVE NEUROPSYCHOLOGY, 2002, 19 (07) : 641 - 652
  • [3] Face processing impairments after encephalitis: amygdala damage and recognition of fear
    Broks, P
    Young, AW
    Maratos, EJ
    Coffey, PJ
    Calder, AJ
    Isaac, CL
    Mayes, AR
    Hodges, JR
    Montaldi, D
    Cezayirli, E
    Roberts, N
    Hadley, D
    [J]. NEUROPSYCHOLOGIA, 1998, 36 (01) : 59 - 70
  • [4] Facial emotion recognition after bilateral amygdala damage: Differentially severe impairment of fear
    Calder, AJ
    Young, AW
    Rowland, D
    Perrett, DI
    Hodges, JR
    Etcoff, NL
    [J]. COGNITIVE NEUROPSYCHOLOGY, 1996, 13 (05) : 699 - 745
  • [5] Impaired recognition of social emotions following amygdala damage
    Adolphs, R
    Baron-Cohen, S
    Tranel, D
    [J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 2002, 14 (08) : 1264 - 1274
  • [6] Impaired auditory recognition of fear and anger following bilateral amygdala lesions
    Scott, SK
    Young, AW
    Calder, AJ
    Hellawell, DJ
    Aggleton, JP
    Johnson, M
    [J]. NATURE, 1997, 385 (6613) : 254 - 257
  • [7] Impaired auditory recognition of fear and anger following bilateral amygdala lesions
    Sophie K. Scott
    Andrew W. Young
    Andrew J. Calder
    Deborah J. Hellawell
    John P. Aggleton
    Michael Johnsons
    [J]. Nature, 1997, 385 : 254 - 257
  • [8] Hypervigilance for fear after basolateral amygdala damage in humans
    D Terburg
    B E Morgan
    E R Montoya
    I T Hooge
    H B Thornton
    A R Hariri
    J Panksepp
    D J Stein
    J van Honk
    [J]. Translational Psychiatry, 2012, 2 : e115 - e115
  • [9] Hypervigilance for fear after basolateral amygdala damage in humans
    Terburg, D.
    Morgan, B. E.
    Montoya, E. R.
    Hooge, I. T.
    Thornton, H. B.
    Hariri, A. R.
    Panksepp, J.
    Stein, D. J.
    van Honk, J.
    [J]. TRANSLATIONAL PSYCHIATRY, 2012, 2 : e115 - e115
  • [10] Bihippocampal damage with emotional dysfunction: Impaired auditory recognition of fear
    Ghika-Schmid, F
    Ghika, J
    Vuilleumier, P
    Assal, G
    Vuadens, P
    Scherer, K
    Maeder, P
    Uske, A
    Bogousslavsky, J
    [J]. EUROPEAN NEUROLOGY, 1997, 38 (04) : 276 - 283