High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells

被引：0
|
作者：
Volker Jäger
Konrad Büssow
Andreas Wagner
Susanne Weber
Michael Hust
André Frenzel
Thomas Schirrmann
机构：
[1] Helmholtz-Zentrum für Infektionsforschung GmbH,Department of Molecular Structural Biology
[2] Institute of Biochemistry,Department of Biotechnology, Technische Universität Braunschweig
[3] Biotechnology and Bioinformatics,undefined
来源：
BMC Biotechnology | / 13卷
关键词：
Recombinant Antibodies; Single Chain Fv; scFv-Fc; ImmunoRNase; Transient Mammalian Protein Production; Serum-free medium;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells
    Jaeger, Volker
    Buessow, Konrad
    Wagner, Andreas
    Weber, Susanne
    Hust, Michael
    Frenzel, Andre
    Schirrmann, Thomas
    BMC BIOTECHNOLOGY, 2013, 13
  • [2] High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension
    Subedi, Ganesh P.
    Johnson, Roy W.
    Moniz, Heather A.
    Moremen, Kelley W.
    Barb, Adam
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2015, (106):
  • [3] Production of recombinant antitumor antibodies by HEK-293 cells
    Deyev S.M.
    Stremovskiy O.A.
    Lukash S.V.
    Karpenko D.V.
    Polyanovsky O.L.
    Petrov R.V.
    Doklady Biochemistry and Biophysics, 2006, 406 (1) : 44 - 46
  • [4] A Multi-Omics Analysis of Recombinant Protein Production in Hek293 Cells
    Dietmair, Stefanie
    Hodson, Mark P.
    Quek, Lake-Ee
    Timmins, Nicholas E.
    Gray, Peter
    Nielsen, Lars K.
    PLOS ONE, 2012, 7 (08):
  • [5] Chorein interacts with cytoskeltal proteins in HEK293 cells
    Deguchi, A.
    Nakamura, M.
    Shiokawa, N.
    Sasaki, N.
    Sano, A.
    JOURNAL OF NEUROCHEMISTRY, 2012, 123 : 105 - 105
  • [6] Optimized Recombinant Production of Secreted Proteins Using Human Embryonic Kidney (HEK293) Cells Grown in Suspension
    Faravelli, Silvia
    Campioni, Matteo
    Palamini, Martina
    Canciani, Anselmo
    Chiapparino, Antonella
    Forneris, Federico
    BIO-PROTOCOL, 2021, 11 (08):
  • [7] Rational design of transient gene expression process with lipoplexes for high-level therapeutic protein production in HEK293 cells
    Lee, Youngji
    Kim, Hyeonkyeong
    Kim, Eunsil
    Park, Soonyong
    Ryu, Kyoung-Hwa
    Lee, Eun Gyo
    PROCESS BIOCHEMISTRY, 2019, 85 : 185 - 194
  • [8] Transient Expression of a Recombinant Monoclonal Antibody in HEK293T Cells
    Mohammadian, Omid
    Rajabibazl, Masoumeh
    Bayat, Hadi
    Rahimpour, Azam
    PHARMACEUTICAL SCIENCES, 2018, 24 (03) : 207 - 212
  • [9] Small molecule chemical additives for enhanced recombinant AAV production in HEK293 cells
    Scarrott, J. M.
    Johari, Y. B.
    Pohle, T. H.
    Liu, P.
    Mayer, A.
    James, D. C.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A105 - A105
  • [10] Process modeling of recombinant adeno-associated virus production in HEK293 cells
    Joiner, Jordan
    Huang, Zhuangrong
    McHugh, Kyle
    Stebbins, Matthew
    Aron, Kathryn
    Borys, Michael
    Khetan, Anurag
    CURRENT OPINION IN CHEMICAL ENGINEERING, 2022, 36
12345