2D/3D image registration on the GPU

We present a method that performs a rigid 2D/3D image registration efficiently on the Graphical Processing Unit (GPU). As one main contribution of this paper, we propose an efficient method for generating realistic DRRs that are visually similar to x-ray images. Therefore, we model some of the electronic post-processes of current x-ray C-arm-systems. As another main contribution, the GPU is used to compute eight intensity-based similarity measures between the DRR and the x-ray image in parallel. A combination of these eight similarity measures is used as a new similarity measure for the optimization. We evaluated the performance and the precision of our 2D/3D image registration algorithm using two phantom models. Compared to a CPU + GPU algorithm, which calculates the similarity measures on the CPU, our GPU algorithm is between three and six times faster. In contrast to single similarity measures, our new similarity measure achieved precise and robust registration results for both phantom models. © 2008 Pleiades Publishing, Ltd.