Inner Ear Organoids: Strengths and Limitations

被引:0
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作者
Giulia Pianigiani
Marta Roccio
机构
[1] Institute for Maternal and Child Health – I.R.C.C.S. “Burlo Garofolo”,Inner Ear Stem Cell Lab, Department Otorhinolaryngology, Head and Neck Surgery
[2] University Hospital Zurich and University of Zurich,undefined
关键词
Human iPSC-derived organoids; Inner ear biology; Hearing loss;
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学科分类号
摘要
Inner ear organoids derived from differentiation of human pluripotent stem cells have recently gained momentum as tools to study inner ear development and developmental defects. An additional exciting aspect about this technology is represented by its translational potential, specifically, the use of organoids to validate therapeutics for hearing and balance restoration on human/patient-specific cells. This latter aspect will be briefly discussed here including opportunities and current limitations.
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页码:5 / 11
页数:6
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