Fabrication and testing of high-performance detection sensor for capillary electrophoresis microchips

被引：0
|
作者：
Lung-Ming Fu
Chia-Yen Lee
Ming-Huei Liao
Che-Hsin Lin
机构：
[1] National Pingtung University of Science and Technology,Department of Materials Engineering
[2] Da-Yeh University,Department of Mechanical and Automation Engineering
[3] National Pingtung University of Science and Technology,Department of Veterinary Medicine
[4] National Sun Yat-sen University,Department of Mechanical and Electro
来源：
Biomedical Microdevices | 2008年 / 10卷
关键词：
Detection sensors; Capillary electrophoresis chip; Lab-on-a-chip;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study presents a new approach for high-performance detection sensors for MEMS-based capillary electrophoresis chips to substitute laser induced fluorescence (LIF) detection systems. The developed sensors easily integrate with well-known microfabrication techniques for glass-based microfluidic devices. Three-dimensional gold electrodes are structured in enveloping side channels by sputtering and patterned using a standard “lift-off” process. The variations in the capacitance between the electrodes in the side channels are measured as different samples and ions pass through the detection region of the capillary electrophoresis separation channel. Samples of beer, white wine and milk are each mixed in different buffer solutions, then successfully separated and detected using the developed device. The proposed high-performance detection sensors have microscale dimensions and provide a critical step towards the realization of the lab-on-a-chip concept.
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页码：73 / 80
页数：7
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