Pathways for the bradykinin B1 receptor-mediated diabetic hyperalgesia in mice

被引：0
|
作者：
B. H. Gabra
P. Sirois
机构：
[1] University of Sherbrooke,Institute of Pharmacology of Sherbrooke, School of Medicine
来源：
Inflammation Research | 2004年 / 53卷
关键词：
Type 1 diabetes; Hyperalgesia; Kinins; Bradykinin B; receptors; Nitric oxide; Substance P; Calcitonin gene-related peptide;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: Experimental evidence has shown that the bradykinin B1 receptor (BKB1-R) is involved in the development of hyperalgesia associated with diabetes since specific BKB1-R antagonists significantly inhibited the hyperalgesic activity observed in streptozotocin (STZ)-mice in thermal nociceptive tests.
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页码：653 / 657
页数：4
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