Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics

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作者
Teck-Hock Toh
Vivian Wee-Yen Tan
Peter Sie-Teck Lau
Andrew Kiyu
机构
[1] Sibu Hospital,Lau King Howe Memorial Children Clinic, Divisional Health Office & Department of Pediatrics
[2] Sibu Hospital,Clinical Research Center
[3] SEGi University Sibu Clinical Campus,Faculty of Medicine
[4] Sarawak State Health Department,Public Health Research Unit
[5] Bintulu Hospital,Department of Pediatrics
[6] University Sarawak Malaysia,Department of Community Medicine & Public Health, Faculty of Medicine & Health Sciences
关键词
Autism spectrum disorder; Developmental disorders; Developmental screening; Accuracy; Early detection; Community;
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摘要
This study determined the accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in detecting toddlers with autism spectrum disorder (ASD) and other developmental disorders (DD) in community mother and child health clinics. We analysed 19,297 eligible toddlers (15–36 months) who had M-CHAT performed in 2006–2011. Overall sensitivities for detecting ASD and all DD were poor but better in the 21 to <27 months and 27–36-month age cohorts (54.5–64.3%). Although positive predictive value (PPV) was poor for ASD, especially the younger cohort, positive M-CHAT helped in detecting all DD (PPV = 81.6%). This suggested M-CHAT for screening ASD was accurate for older cohorts (>21 months) and a useful screening tool for all DD.
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页码:28 / 35
页数:7
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