Formulation and Lyoprotection of Poly(Lactic Acid-Co-Ethylene Oxide) Nanoparticles: Influence on Physical Stability and In Vitro Cell Uptake

被引：0
|
作者：
Fanny De Jaeghere
Eric Allémann
Jean-Christophe Leroux
Wim Stevels
Jan Feijen
Eric Doelker
Robert Gurny
机构：
[1] University of Geneva,School of Pharmacy
[2] University of Montreal,Faculty of Pharmacy
[3] University of Twente,Faculty of Chemical Technology
来源：
Pharmaceutical Research | 1999年 / 16卷
关键词：
nanoparticles; poly(lactic acid); poly(lactic acid-; -ethylene oxide); freeze-drying; stability; flow cytometry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To investigate the feasibility of producing freeze-dried poly-(ethylene oxide) (PEO)-surface modified nanoparticles and to study their ability to avoid the mononuclear phagocytic system (MPS), as a function of the PEO chain length and surface density.
引用
收藏
页码：859 / 866
页数：7
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