Frequency and potential application of HLA antibodies from pregnant women in Mumbai

被引：0
|
作者：
U. Shankarkumar
S. C. Gupte
S. S. Gupte
S. V. Pednkar
K. Ghosh
D. Mohanty
机构：
[1] Institute of Immunohaematology,HLA Department
来源：
Journal of Biosciences | 1998年 / 23卷
关键词：
HLA; anti HLA antibodies; antenatal sera;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Antenatal sera from 1334 pregnant women attending the Nowrojee B J Wadia Maternity Hospital and KEM Hospital in Parel, Mumbai were collected and screened for anti HLA A and B antibodies to produce an indigenous HLA tissue typing tray. One hundred and sixty three sera (12.2%) were found positive for HLA antibodies. Nonetheless, the percentage of positive sera were almost the same in women of different parity. Moreover, the incidence of anti-HLA antibodies was correlated with the allelic frequencies in the Maharastrian population. Thus in India, collection and screening of sera from pregnant females is a simple and cost-effective method of acquiring polyclonal sera for routine use in tissue typing.
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页码：601 / 604
页数：3
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