Human ex-vivo oral tissue imaging using spectral domain polarization sensitive optical coherence tomography

被引：0

作者：

Priyanka Sharma

Yogesh Verma

Khageswar Sahu

Sudhir Kumar

Amit V Varma

Jyoti Kumawat

Pradeep Kumar Gupta

机构：

[1] Raja Ramanna Centre for Advanced Technology,Laser Biomedical Applications Section

[2] Homi Bhabha National Institute,Wellman Center for Photomedicine

[3] Harvard Medical School and Massachusetts General Hospital,undefined

[4] Sri Aurobindo Medical College and P. G. Institute,undefined

来源：

Lasers in Medical Science | 2017年 / 32卷

关键词：

Optical coherence tomography; Spectral domain polarization sensitive optical coherence tomography; Oral cancer; Collagen; Submucosal fibrosis; Trichrome staining;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We report the use of spectral domain polarization sensitive optical coherence tomography for ex-vivo imaging of human oral mandibular tissue samples. Our results show that compared to the changes observed in the epithelium thickness and the decay constant of A-scan intensity profile, a much larger degree of change was observed in the phase retardation for tissue sites progressing from normal to the malignant state. These results suggest that monitoring of tissue retardance can help in better differentiation of normal and cancerous oral tissue sites.

引用

页码：143 / 150

页数：7

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