The SUMO protease SENP7 is a critical component to ensure HP1 enrichment at pericentric heterochromatin

被引：0
|
作者：
Christèle Maison
Kelly Romeo
Delphine Bailly
Marion Dubarry
Jean-Pierre Quivy
Geneviève Almouzni
机构：
[1] Institut Curie,
[2] Centre de Recherche,undefined
[3] Centre National de la Recherche Scientifique (CNRS),undefined
[4] Unité Mixte de Recherche UMR218,undefined
来源：
Nature Structural & Molecular Biology | 2012年 / 19卷
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摘要：
SUMOylation targets HP1α to pericentric heterochromatin, but the enzyme responsible for removing the SUMO molecule from HP1α has not been determined. SENP7 is now identified as the factor that deconjugates SUMO, promoting retention of HP1α at these domains.
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页码：458 / 460
页数：2
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