Long-term outcomes from sepsis

被引:71
|
作者
Yende S. [1 ]
Angus D.C. [1 ]
机构
[1] Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261
关键词
Severe Sepsis; Acute Respiratory Distress Syndrome; Critical Illness; Continuous Renal Replacement Therapy; Chronic Health Condition;
D O I
10.1007/s11908-007-0059-3
中图分类号
学科分类号
摘要
Long-term mortality following severe sepsis is high, and fewer than half of patients who experience severe sepsis are alive at 1 year. Mechanisms underlying increased long-term mortality remain poorly understood. Animal and human studies suggest that abnormalities of the innate immune system may contribute to increased long-term mortality. This review article examines the epidemiology and potential mechanisms underlying long-term outcomes from sepsis and challenges to conducting long-term outcome studies in the critically ill. Copyright © 2007 by Current Medicine Group LLC.
引用
收藏
页码:382 / 386
页数:4
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