Stairway Plot 2: demographic history inference with folded SNP frequency spectra (vol 21, 280, 2020)

被引：0

作者：

Liu, Xiaoming ^{[1
]}

Fu, Yun-Xin ^{[2
]}

机构：

[1] Univ S Florida, USF Genom & Coll Publ Hlth, Tampa, FL 33620 USA

[2] Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Biostat & Data Sci, Houston, TX 77030 USA

来源：

GENOME BIOLOGY | 2020年 / 21卷 / 01期

关键词：

D O I：

10.1186/s13059-020-02243-5

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Inferring the demographic histories of populations has wide applications in population, ecological, and conservation genomics. We present Stairway Plot 2, a cross-platform program package for this task using SNP frequency spectra. It is based on a nonparametric method with the capability of handling folded SNP frequency spectra (that is, when the ancestral alleles of the SNPs are unknown) of thousands of samples produced with genotyping-by-sequencing technologies; therefore, it is particularly suitable for nonmodel organisms. © 2020, The Author(s).

引用

页数：1