Prohibitin mutations are uncommon in prostate cancer families linked to chromosome 17q

被引:0
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作者
K A White
E M Lange
A M Ray
K J Wojno
K A Cooney
机构
[1] University of Michigan Medical School,Department of Internal Medicine
[2] University of North Carolina,Departments of Genetics and Biostatistics
[3] University of Michigan Medical School,Department of Urology
关键词
hereditary cancer; linkage studies; sequence analysis;
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学科分类号
摘要
Background: Linkage studies have provided evidence for a prostate cancer susceptibility locus on chromosome 17q. The mitochondrial protein prohibitin (PHB) is a plausible candidate gene based on its chromosomal location (17q21) and known function.
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页码:298 / 302
页数:4
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