Soluble CX3CL1-expressing retinal pigment epithelium cells protect rod photoreceptors in a mouse model of retinitis pigmentosa

被引：0
|
作者：
Eric D. Jong
Sabiha Hacibekiroglu
Lily Guo
Evan Sawula
Biao Li
Chengjin Li
Margaret T. Ho
Molly S. Shoichet
Valerie A. Wallace
Andras Nagy
机构：
[1] Lunenfeld-Tanenbaum Research Institute,Institute of Medical Science, Faculty of Medicine
[2] Sinai Health System,Institute of Biomedical Engineering
[3] University of Toronto,Terrence Donnelly Centre for Cellular & Biomolecular Research
[4] University of Toronto,Department of Chemical Engineering and Applied Chemistry
[5] University of Toronto,Department of Chemistry
[6] University of Toronto,Donald K. Johnson Eye Institute, Krembil Research Institute
[7] University of Toronto,Department of Laboratory Medicine and Pathobiology
[8] University Health Network,Department of Ophthalmology and Vision Sciences
[9] University of Toronto,Australian Regenerative Medicine Institute
[10] University of Toronto,Department of Obstetrics & Gynecology, Faculty of Medicine
[11] Monash University,undefined
[12] University of Toronto,undefined
来源：
Stem Cell Research & Therapy | / 14卷
关键词：
Retinal degeneration; Retinitis pigmentosa; Cell therapy; Gene therapy; Microglia activation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 27 条
  • [1] Soluble CX3CL1-expressing retinal pigment epithelium cells protect rod photoreceptors in a mouse model of retinitis pigmentosa
    Jong, Eric D.
    Hacibekiroglu, Sabiha
    Guo, Lily
    Sawula, Evan
    Li, Biao
    Li, Chengjin
    Ho, Margaret T.
    Shoichet, Molly S.
    Wallace, Valerie A.
    Nagy, Andras
    STEM CELL RESEARCH & THERAPY, 2023, 14 (01)
  • [2] Transplantation of CX3CL1-expressing Mesenchymal Stem Cells Provides Neuroprotective and Immunomodulatory Effects in a Rat Model of Retinal Degeneration
    Huang, Libin
    Xu, Wei
    Xu, Guoxing
    OCULAR IMMUNOLOGY AND INFLAMMATION, 2013, 21 (04) : 276 - 285
  • [3] Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa
    Wang, Sean K.
    Xue, Yunlu
    Rana, Parimal
    Hong, Christin M.
    Cepko, Constance L.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (20) : 10140 - 10149
  • [4] Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa
    Wang, Sean K.
    Xue, Yunlu
    Rana, Parimal
    Hong, Christin
    Cepko, Constance
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [5] Intratracheal Delivery of CX3CL1-Expressing Mesenchymal Stem Cells to Multiple Lung Tumors
    Xin, Hong
    Sun, Ruowen
    Kanehira, Masahiko
    Takahata, Takenori
    Itoh, Jugoh
    Mizuguchi, Hiroyuki
    Saijo, Yasuo
    MOLECULAR MEDICINE, 2009, 15 (9-10) : 321 - 327
  • [6] Intratracheal Delivery of CX3CL1-Expressing Mesenchymal Stem Cells to Multiple Lung Tumors
    Hong Xin
    Ruowen Sun
    Masahiko Kanehira
    Takenori Takahata
    Jugoh Itoh
    Hiroyuki Mizuguchi
    Yasuo Saijo
    Molecular Medicine, 2009, 15 : 321 - 327
  • [7] Cell therapy with pluripotent stem cells differentiated to retinal pigment epithelium and photoreceptor cells in a rat model of Retinitis Pigmentosa
    Fontrodona Montals, Laura
    Riera, Marina
    Salas Torras, Anna
    Seriola, Anna
    Munoz, Yolanda
    Mora, Diana
    Angel Zapata, Miguel
    Veiga, Anna
    Garcia-Arumi, Jose
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
  • [8] Exercise protects against retinal degeneration and retinal pigment epithelium (RPE) stress in the RHOtvrm4/+ mouse model of retinitis pigmentosa
    Zhang, Xian
    Girardot, Preston
    Sellers, Jana T.
    Wu, Wenfei
    Skelton, Henry
    Nickerson, John M.
    Pardue, Machelle T.
    Boatright, Jeffrey H.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [9] Microglial Phagocytosis and Activation Underlying Photoreceptor Degeneration is Regulated by CX3CL1-CX3CR1 Signaling in a Mouse Model of Retinitis Pigmentosa
    Zabel, Matthew K.
    Zhao, Lian
    Zhang, Yikui
    Gonzalez, Shaimar R.
    Ma, Wenxin
    Wang, Xu
    Fariss, Robert N.
    Wong, Wai T.
    GLIA, 2016, 64 (09) : 1479 - 1491
  • [10] Transplantation of CX3CL1-expressing Mesenchymal Stem Cells Provides Neuroprotective and Immunomodulatory Effects in a Rat Model of Retinal Degeneration' (vol 21, pg 276, 2013)
    Huang, Libin
    Xu, Wei
    Xu, Guoxing
    OCULAR IMMUNOLOGY AND INFLAMMATION, 2015, 23 (06) : 470 - 470
123