Effect of Periodic Disinfection on Persisters in a One-Dimensional Biofilm Model

被引：0
|
作者：
N. G. Cogan
Barbara Szomolay
Martin Dindos
机构：
[1] Florida State University,Department of Mathematics
[2] University of Warwick,Mathematics Institute
[3] The University of Edinburgh,Maxwell Institute for Mathematical Sciences
来源：
Bulletin of Mathematical Biology | 2013年 / 75卷
关键词：
Persister; Biofilm;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
It is well known that disinfection methods that successfully kill suspended bacterial populations often fail to eliminate bacterial biofilms. Recent efforts to understand biofilm survival have focused on the existence of small, but very tolerant, subsets of the bacterial population termed persisters. In this investigation, we analyze a mathematical model of disinfection that consists of a susceptible-persister population system embedded within a growing domain. This system is coupled to a reaction-diffusion system governing the antibiotic and nutrient.
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页码：94 / 123
页数：29
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