Phase I study and preclinical efficacy evaluation of the mTOR inhibitor sirolimus plus gemcitabine in patients with advanced solid tumours

被引:0
|
作者
J Martin-Liberal
M Gil-Martín
M Sáinz-Jaspeado
N Gonzalo
R Rigo
H Colom
C Muñoz
O M Tirado
X García del Muro
机构
[1] The Royal Marsden Hospital,Department of Immunology
[2] Institut Català d'Oncologia L'Hospitalet,undefined
[3] Genitourinary Tumors,undefined
[4] Sarcoma and Melanoma Unit,undefined
[5] Genetics and Pathology,undefined
[6] Rudbeck Laboratory,undefined
[7] Uppsala University,undefined
[8] Institut Català d'Oncologia L'Hospitalet,undefined
[9] Laboratori de Farmacocinètica,undefined
[10] Hospital de Bellvitge,undefined
[11] Àrea de Bioquímica i Biologia Molecular,undefined
[12] Universitat de Barcelona,undefined
[13] Facultat de Farmàcia,undefined
[14] Institut d'Investigació Biomèdica de Bellvitge (IDIBELL),undefined
[15] Laboratori d'Oncología Molecular,undefined
[16] Sarcoma Research Group,undefined
来源
British Journal of Cancer | 2014年 / 111卷
关键词
gemcitabine; sirolimus; rapamycin; mTOR; phase I;
D O I
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中图分类号
学科分类号
摘要
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页码:858 / 865
页数:7
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