This article reviews the evidence of the effects of atypical antipsychotics other than clozapine in patients with schizophrenia that is resistant to treatment with conventional agents. Clozapine remains the one drug with proven efficacy in patients with severely refractory symptoms. However, while the drug is modestly effective in 30 to 70% of these patients, there are many who are either intolerant of, or unresponsive to, it.
机构:
Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Geisinger Commonwealth Sch Med, Dept Med Educ, 525 Pine St, Scranton, PA 18509 USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Warnick, Justina A.
Gifeisman, Rachel I.
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Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Gifeisman, Rachel I.
Joshi, Khevna P.
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Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Joshi, Khevna P.
Roe, Sophie A.
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Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Roe, Sophie A.
Hiciano, Rick A.
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Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Hiciano, Rick A.
Conroy, Christopher P.
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Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
Conroy, Christopher P.
Zahedi, Sohrab
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Geisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
State Correct Inst, Centur Hlth, Waymart, PA USA
Univ Connecticut, Sch Med, Farmington, CT USAGeisinger Commonwealth Sch Med, Dept Med Educ, Scranton, PA USA
机构:
UT Southwestern Med Ctr, Dallas, TX USAUT Southwestern Med Ctr, Dallas, TX USA
Vas, Collin
Jain, Ayush
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机构:
Shri Ram Sch, Gurgaon, Haryana, IndiaUT Southwestern Med Ctr, Dallas, TX USA
Jain, Ayush
Trivedi, Mili
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Colleyville Heritage High Sch, Colleyville, TX USAUT Southwestern Med Ctr, Dallas, TX USA
Trivedi, Mili
Jha, Manish Kumar
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UT Southwestern Med Ctr, Ctr Depress Res & Clin Care, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUT Southwestern Med Ctr, Dallas, TX USA
Jha, Manish Kumar
Mathew, Sanjay J.
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机构:
Baylor Coll Med, Michael E DeBakey VA Med Ctr, Menninger Dept Psychiat & Behav Sci, Menninger Clin, Houston, TX USAUT Southwestern Med Ctr, Dallas, TX USA